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Inpatient deaths by medical service: characteristics in a comprehensive cancer centre
  1. Sebastiano Mercadante1,
  2. Alessio Lo Cascio2 and
  3. Alessandra Casuccio3
  1. 1Pain Relief and Supportive Care, Casa di Cura La Maddalena, Palermo, Italy
  2. 2Pain Relief and Supportive Care, Private Hospital La Maddalena, Palermo, Italy
  3. 3Department of Health Promotion, University of Palermo, Palermo, Italy
  1. Correspondence to Professor Sebastiano Mercadante, Pain Relief and Supportive Care, Casa di Cura La Maddalena, 90145 Palermo, Italy; 03sebelle{at}gmail.com

Abstract

Aim To examine the intensity of care in the last 3 days of life in different medical settings of a comprehensive cancer centre.

Methods In this retrospective study, the charts of patients who died in hospital from July 2019 to June 2023 were reviewed. The units taken into consideration were acute palliative care unit (APCU), oncology (ONC) and haematology (HEM), which included also the transplantation unit. Age, gender, diagnosis, Karnofsky or Eastern Cooperative Oncology Group, drugs used in the last 3 days of life, respiratory support, transfusion, parenteral nutrition, imaging studies, blood gas analysis, biochemistry, consultations and endoscopy were retrieved.

Results Data on 177 patients who died in the period taken into consideration were reviewed. APCU was characterised by more frequent use of opioids, midazolam and scopolamine butylbromide. On the other side, HEM was characterised by higher use of vasoactive drugs, antibiotics, transfusions, imaging studies, growth factors, consultations, biochemistry, blood gas analysis, parenteral nutrition and ventilatory support. ONC was characterised by the larger use of anticoagulants and ventilatory support.

Conclusion A more aggressive treatment was performed in HEM, as denoted by a large use of life-sustaining treatments and investigations. Taken together, these data show that the way to die is different depending on the setting of care. End-of-life funnel is similar for every dying patient and choices should be based on short prognosis and expectation rather than on disproportionate and afinalistic treatments.

  • Cancer
  • Clinical decisions
  • Drug administration
  • End of life care
  • Haematological disease

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Footnotes

  • Twitter @#SebMercadante

  • Contributors SM designed and wrote the study. ALC managed the data. AC was responsible for the statistics. All authors gave their final approval.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.