Background The COVID-19 pandemic has led to many challenges such as increased number of patients and the risk of the disease progress in the world’s healthcare systems, especially nursing. The capacity of technology can help nursing in such conditions. The aim of this study was to explore the lived experiences of patients with COVID-19 with home care by using telenursing.

Methods The present study is a qualitative research conducted using the descriptive phenomenological method. The participants were selected using purposive sampling method and considering the inclusion and exclusion criteria. After obtaining ethical approval, data were collected through semistructured interviews. Open-ended questions and follow-up were used in the interviews. The interviews were conducted using Skype application and telephone. All data were recorded, and MAXQDA software was used to manage the data. Data analysis was performed using Colaizzi’s seven-step method. Lincoln and Guba’s criteria were used to evaluate the trustworthiness of the data.

Results The main themes and their subthemes included ‘facilitators’ (improvement of relationships, adequate education and counselling, adequate care and support, improvement and promotion of health) and ‘barriers’ (lack of previous knowledge and experience, infrastructure problems, confusion in hospital programmes and the pressure caused by the COVID-19 pandemic).

Conclusion Given the potential capacity of telenursing, strong field studies are recommended to be conducted in this area. The results of such studies can contribute to the rapid and serious use of telenursing in the area of care, education, support, follow-up and counselling of patients.