Diagnosis and classification of optic neuritis

…, J Hooker, JY Hor, W Howlett… - The Lancet …, 2022 - thelancet.com
There is no consensus regarding the classification of optic neuritis, and precise diagnostic
criteria are not available. This reality means that the diagnosis of disorders that have optic …

Konzo, an epidemic upper motor neuron disease studied in Tanzania

WP Howlett, GR Brubaker, N Mlingi, H Rosling - Brain, 1990 - academic.oup.com
An epidemic of spastic paraparesis was studied in a drought-affected rural area of Tarime
district in northern Tanzania. The uniform clinical findings in 39 cases, aged 4–46 yrs …

Neurological disorders in HIV in Africa: a review

WP Howlett - African health sciences, 2019 - ajol.info
Background: Neurological disorders in HIV infection are a common cause of morbidity and
mortality. The aim of this paper is to provide a narrative overview of up to date information …

[HTML][HTML] Neurosyphilis in Africa: a systematic review

M Marks, JN Jarvis, W Howlett… - PLoS neglected tropical …, 2017 - journals.plos.org
Introduction Neurological involvement is one of the most important clinical manifestations of
syphilis and neurological disease occurs in both early and late syphilis. The impact of HIV co …

Konzo: a distinct disease entity with selective upper motor neuron damage.

T Tylleskär, WP Howlett, HT Rwiza… - Journal of Neurology …, 1993 - jnnp.bmj.com
Two Tanzanian patients with konzo were severely disabled by a non-progressive spastic
paraparesis, since the sudden onset during an epidemic six years earlier. At the time of …

[HTML][HTML] Prevalence, patterns, and factors associated with peripheral neuropathies among diabetic patients at tertiary Hospital in the Kilimanjaro Region: descriptive …

…, IA Lyaruu, D Marieke, ER Shao, W Howlett - International journal of …, 2019 - hindawi.com
Objective. Diabetic peripheral neuropathy (DPN) is a common microvascular complication of
diabetes mellitus (DM) and may progress to diabetic foot, which frequently leads to …

The prevalence of neurological disorders in older people in T anzania

…, WK Gray, E Aris, G Orega, W Howlett… - Acta Neurologica …, 2013 - Wiley Online Library
Objectives There are few data on neurological disorders prevalence from low‐and middle‐
income countries, particularly sub‐S aharan A frica (SSA) and none specific to the A frican …

[HTML][HTML] Screening for HIV-associated neurocognitive disorder (hand) in adults aged 50 and over attending a government HIV clinic in Kilimanjaro, Tanzania …

J Kellett-Wright, A Flatt, P Eaton, S Urasa, W Howlett… - AIDS and Behavior, 2021 - Springer
Validated screening tools for HIV-associated neurocognitive disorders (HAND) are lacking
for the newly emergent ageing population of people living with HIV (PLWH) in sub-Saharan …

Postischemic treatment with calpain inhibitor MDL 28170 ameliorates brain damage in a gerbil model of global ischemia

PA Li, W Howlett, QP He, H Miyashita, M Siddiqui… - Neuroscience …, 1998 - Elsevier
The newly-developed calpain inhibitor, MDL 28170 penetrates the blood–brain barrier and
inhibits brain cysteine protease activity after systemic administration. This experiment was …

Guillain‐Barré syndrome in northern Tanzania: a comparison of epidemiological and clinical findings with western Norway

WP Howlett, CA Vedeler, H Nyland… - Acta neurologica …, 1996 - Wiley Online Library
To study Guillain‐Barré syndrome (GBS), the clinical files of GBS patients, 59 in northern
Tanzania (1984–1992) and 56 in western Norway (1980–1992), were retrospectively …