[HTML][HTML] Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart
SS Hothi, IS Gurung, JC Heathcote, Y Zhang… - … -European Journal of …, 2008 - Springer
The recently described exchange protein directly activated by cAMP (Epac) has been
implicated in distinct protein kinase A-independent cellular signalling pathways. We …
implicated in distinct protein kinase A-independent cellular signalling pathways. We …
[HTML][HTML] Arrhythmogenic substrate and its modification by nicorandil in a murine model of long QT type 3 syndrome
SS Hothi, SW Booth, IN Sabir, MJ Killeen… - Progress in biophysics …, 2008 - Elsevier
The gain-of-function Scn5a+/ΔKPQ mutation in the cardiac Na+ channel causes human long
QT type 3 syndrome (LQT3) associated with ventricular arrhythmogenesis. The KATP …
QT type 3 syndrome (LQT3) associated with ventricular arrhythmogenesis. The KATP …
[HTML][HTML] A Phase 2a cohort expansion study to assess the safety, tolerability, and preliminary efficacy of CXD101 in patients with advanced solid-organ cancer …
SW Booth, TA Eyre, J Whittaker, L Campo, LM Wang… - BMC cancer, 2021 - Springer
Abstract Background This Phase 2a dose expansion study was performed to assess the
safety, tolerability and preliminary efficacy of the maximum tolerated dose of the oral histone …
safety, tolerability and preliminary efficacy of the maximum tolerated dose of the oral histone …
Pictorial prescribing reduces fentanyl drug administration errors: a simulated controlled study
SW Booth, M Gloag, S Kinna, A Bell… - BMJ Supportive & …, 2017 - spcare.bmj.com
Objectives Transmucosal fentanyl is used to treat transient exacerbations of cancer pain.
Several immediate release products are available, presented as intranasal sprays …
Several immediate release products are available, presented as intranasal sprays …