Ewing sarcoma (ES) is an aggressive sarcoma of bone and soft tissue occurring at any age
with a peak incidence in adolescents and young adults. The treatment of ES relies on a …

Peripheral neuroblastic tumours (PNTs), a family of tumours arising in the embryonal
remnants of the sympathetic nervous system, account for 7–10% of all tumours in children. In …

BACKGROUND The authors reviewed their institutional experience regarding adult patients
with Wilms' tumor (WT) to assess their clinical characteristics and compliance with respect to …

Background Immunotherapy with the chimeric anti-GD2 monoclonal antibody dinutuximab,
combined with alternating granulocyte-macrophage colony-stimulating factor and …

Background High-dose chemotherapy with haemopoietic stem-cell rescue improves event-
free survival in patients with high-risk neuroblastoma; however, which regimen has the …

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase predominantly expressed in
the developing nervous system. Recently, mutated ALK has been identified as a major …

Purpose: The aim of this study was to avoid radio-therapy and to induce an objective
response in children with low-grade glioma (LGG) using a simple chemotherapy regimen …

To the Editor: This report assesses the impact of the COVID-19 pandemic on pediatric
cancer patients over an 8-week period elapsing from the day of the Italian outbreak …

Abstract Purpose: Fenretinide (4HPR), a synthetic retinoid, induces apoptosis in
neuroblastoma cells. A Phase I study in children with neuroblastoma was designed to …

Hyperfractionated Accelerated Radiotherapy in the Milan Strategy for Metastatic Medulloblastoma
Page 1 Hyperfractionated Accelerated Radiotherapy in the Milan Strategy for Metastatic …