Few case-finding instruments are available to community healthcare professionals. This
review aims to identify short, valid instruments that detect older community-dwellers risk of …

Dominantly inherited Alzheimer's disease (DIAD) causes predictable biological changes
decades before the onset of clinical symptoms, enabling testing of interventions in the …

Background: This randomized, double-blind, placebo-controlled trial examined the efficacy
and safety of risperidone in the treatment of aggression, agitation, and psychosis in elderly …

Aims/hypothesis The aim was to investigate the relationship between severe hypoglycaemia
and cognitive impairment in older patients with diabetes. Methods A sample of 302 diabetic …

Objective: To investigate whether supplementing older men with vitamins B12, B6, and folic
acid improves cognitive function. Methods: The investigators recruited 299 community …

Objective: To determine whether the prevalence of dementia, depression and/or disability in
older diabetic subjects warrants an active screening approach by diabetes health care …

Background The identification of people at risk of cognitive impairment is essential for
improving recruitment in secondary prevention trials of Alzheimer's disease. We aimed to …

Eleven early-onset dementia families, all with affected individuals who have either
presented clinical symptoms of early onset familial Alzheimer's disease (EOFAD) or have …

Aims/hypothesis Diabetes is associated with an increased risk of dementia but the reasons
for this association are unclear because there are many potential mechanisms. We explored …

Subjective memory complaint is common in later life. Its relationship to future risk of
dementia is unclear, although many reports have found a positive association. We designed …