Purpose Endometrial cancers have long been divided into estrogen-dependent type I and
the less common clinically aggressive estrogen-independent type II. Little is known about …

Somatic mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor
(EGFR) gene are reportedly associated with sensitivity of lung cancers to gefitinib (Iressa) …

Objectives: The metabolic dysfunction driven by obesity, including hyperglycemia and
dyslipidemia, increases risk for developing at least 13 cancer types. The concept of …

Background Endometriosis is a risk factor for epithelial ovarian cancer; however, whether
this risk extends to all invasive histological subtypes or borderline tumours is not clear. We …

Inflammation has been implicated in ovarian carcinogenesis. However, studies investigating
the association between pelvic inflammatory disease (PID) and ovarian cancer risk are few …

TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed∼ 480 …

Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

Background The understanding of ovarian cancer pathogenesis has recently shifted to
recognize distinct changes in how ovarian cancer histotypes are defined. Using the 2014 …

Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome …

To identify common alleles associated with different histotypes of epithelial ovarian cancer
(EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …