Factors associated with older people's emergency department attendance towards the end of life: a systematic review

AE Bone, CJ Evans, SN Etkind… - European journal of …, 2019 - academic.oup.com
Background Emergency department (ED) attendance for older people towards the end of life
is common and increasing, despite most preferring home-based care. We aimed to review …

Early and empirical high-dose cryoprecipitate for hemorrhage after traumatic injury: the CRYOSTAT-2 randomized clinical trial

R Davenport, N Curry, EE Fox, H Thomas, J Lucas… - Jama, 2023 - jamanetwork.com
Importance Critical bleeding is associated with a high mortality rate in patients with trauma.
Hemorrhage is exacerbated by a complex derangement of coagulation, including an acute …

How common are palliative care needs among older people who die in the emergency department?

T Beynon, B Gomes, FEM Murtagh… - Emergency Medicine …, 2011 - emj.bmj.com
Objective To determine the prevalence and nature of palliative care needs in people aged
65 years or more (65+) who die in emergency departments (EDs). Methods This was a …

Clinical audit does not work, is quality improvement any better?

A Boyle, J Keep - British Journal of Hospital Medicine, 2018 - magonlinelibrary.com
This article reviews the history of clinical audit and appraises its effectiveness. It discusses
why audit can be ineffective in improving care and makes proposals to remove these …

A case-controlled comparison of thrombolysis outcomes between wake-up and known time of onset ischemic stroke patients

D Manawadu, S Bodla, J Jarosz, J Keep, L Kalra - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Wake-up ischemic stroke (WUIS) patients are not thrombolysed
even if they meet other criteria for treatment. We hypothesized that patients with WUIS …

An observational study of thrombolysis outcomes in wake-up ischemic stroke patients

D Manawadu, S Bodla, J Keep, J Jarosz, L Kalra - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Wake-up ischemic stroke (WUIS) patients are not eligible for
thrombolysis; the a priori hypothesis was that thrombolysis of selected WUIS patients who …

[HTML][HTML] Safety and clinical outcome of thrombolysis in ischaemic stroke using a perfusion CT mismatch between 3 and 6 hours

LK Sztriha, D Manawadu, J Jarosz, J Keep, L Kalra - PloS one, 2011 - journals.plos.org
Objective It may be possible to thrombolyse ischaemic stroke (IS) patients up to 6 h by using
penumbral imaging. We investigated whether a perfusion CT (CTP) mismatch can help to …

Paracetamol toxicity: what would be the implications of a change in UK treatment guidelines?

DJ McQuade, PI Dargan, J Keep, DM Wood - European journal of clinical …, 2012 - Springer
Background Treatment of single-time-point ingestion acute paracetamol (acetaminophen)
poisoning with N-acetylcysteine (NAC) is guided by plotting a timed plasma paracetamol …

Influence of age on thrombolysis outcome in wake-up stroke

D Manawadu, S Bodla, J Keep, L Kalra - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Thrombolysis in patients> 80 years remains controversial; we
hypothesized that> 80-year-old patients with wake-up ischemic stroke (WUIS) will benefit …

Time matters: antibiotic timing in sepsis and septic shock

D Youkee, W Hulme, T Roberts, R Daniels… - Critical care …, 2016 - journals.lww.com
2. Foran M, Ahn R, Novik J, et al: Prevalence of undiagnosed hypoxemia in adults and
children in an under-resourced district hospital in Zambia. Int J Emerg Med 2010; 3: 351 …