Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology

PM Seferović, MC Petrie, GS Filippatos… - European journal of …, 2018 - Wiley Online Library
The coexistence of type 2 diabetes mellitus (T2DM) and heart failure (HF), either with
reduced (HFrEF) or preserved ejection fraction (HFpEF), is frequent (30–40% of patients) …

Cardiovascular effects of treatment with the ketone body 3-hydroxybutyrate in chronic heart failure patients

R Nielsen, N Møller, LC Gormsen, LP Tolbod… - Circulation, 2019 - Am Heart Assoc
Background: Myocardial utilization of 3-hydroxybutyrate (3-OHB) is increased in patients
with heart failure and reduced ejection fraction (HFrEF). However, the cardiovascular effects …

Effect of liraglutide, a glucagon‐like peptide‐1 analogue, on left ventricular function in stable chronic heart failure patients with and without diabetes (LIVE)—a …

A Jorsal, C Kistorp, P Holmager… - European journal of …, 2017 - Wiley Online Library
Aims To determine the effect of the glucagon‐like peptide‐1 analogue liraglutide on left
ventricular function in chronic heart failure patients with and without type 2 diabetes …

Ketone body infusion with 3‐hydroxybutyrate reduces myocardial glucose uptake and increases blood flow in humans: a positron emission tomography study

LC Gormsen, M Svart, HH Thomsen… - Journal of the …, 2017 - Am Heart Assoc
Background High levels of ketone bodies are associated with improved survival as observed
with regular exercise, caloric restriction, and—most recently—treatment with sodium …

Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure

M Halbirk, H Nørrelund, N Møller… - American Journal …, 2010 - journals.physiology.org
The incretin hormone glucagon-like peptide-1 (GLP-1) and its analogs are currently
emerging as antidiabetic medications. GLP-1 improves left ventricular ejection fraction …

A systematic review of biomarkers in the diagnosis of infective endocarditis

MG Snipsøyr, M Ludvigsen, E Petersen… - International journal of …, 2016 - Elsevier
Timely diagnosis of bacterial infective endocarditis (IE) is crucial, as mortality remains high
in this severe bacterial infection, currently without any distinct biological markers. Our goal …

Electromechanical mapping for detection of myocardial viability in patients with ischemic cardiomyopathy

HE Bøtker, JF Lassen, F Hermansen, H Wiggers… - Circulation, 2001 - Am Heart Assoc
Background—We evaluated the ability of electromechanical mapping of the left ventricle to
distinguish between nonviable and viable myocardium in patients with ischemic …

Prevalence and prognostic significance of hyponatraemia in outpatients with chronic heart failure

L Balling, M Schou, L Videbæk… - European journal of …, 2011 - Wiley Online Library
Aim Hyponatraemia has been reported to be a potent predictor of poor outcome in patients
hospitalized for heart failure (HF). The aim of the study was to determine the prevalence and …

SGLT2 inhibition does not affect myocardial fatty acid oxidation or uptake, but reduces myocardial glucose uptake and blood flow in individuals with type 2 diabetes: a …

KM Lauritsen, BRR Nielsen, LP Tolbod… - Diabetes, 2021 - Am Diabetes Assoc
Sodium–glucose cotransporter 2 (SGLT2) inhibition reduces cardiovascular morbidity and
mortality in individuals with type 2 diabetes. Beneficial effects have been attributed to …

Increased amounts of collagenase and gelatinase in porcine myocardium following ischemia and reperfusion

CC Danielsen, H Wiggers, HR Andersen - Journal of molecular and cellular …, 1998 - Elsevier
We studied the presence of collagen degrading enzymes (matrix metalloproteinases, MMPs)
in porcine myocardium following ischemia and late reperfusion. In nine pigs, left anterior …