Respiratory disease accounts for a large proportion of emergency admissions to hospital
and diseaseassociated mortality. Genetic association studies demonstrate a link between …

Background Community-acquired pneumonia (CAP) is considered the leading cause of
death from infectious disease in developed countries, while complications of CAP-sepsis …

IREB2 is a gene that produces iron regulatory protein 2 (IRP2), which is critical to
intracellular iron homeostasis and which relates to the rate of cellular proliferation. IREB2 …

Materials and Methods: This was a non-randomised parallel group prospective
observational study. Hospitalised and community-treated CF adults receiving IVAT for APE …

Health in the UK has stopped improving and progress in reducing health inequalities has
been negative. 1 The COVID-19 pandemic has further emphasised poorer outcomes in …

Methods A mixed qualitative and quantitative questionnaire was devised (see online
supplemental appendix 1). All hospices in England, Scotland and Wales with an inpatient …

ABSTRACT UK guidelines recommend that discussions about organ and tissue donation
are conducted as part of end-of-life care. However, there are several barriers to discussing …

Abstract Introduction The End of Life Care in Advanced Kidney Disease Framework
suggests that renal units should create a renal supportive care register (RSCR) to promote …

Background The aim of the Renal Supportive Care Register (RSCR) at Birmingham
Heartlands Hospital is to identify patients who are requiring dialysis with a prognosis of less …

Background: Single nucleotide polymorphisms (SNPs) of family with sequence familiarity 13,
member A (FAM13A), hedgehog interacting protein (HHIP) and iron regulatory binding …