Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis has been found in some
psychiatric disorders, especially in older patients with severe depression. Altered feedback …

The peptide hormone ghrelin is important for both homeostatic and hedonic eating
behaviors, and its orexigenic actions occur mainly via binding to the only known ghrelin …

Mood is the changing expression of emotion and can be described as a spectrum. The
outermost ends of this spectrum highlight two states, the lowest low, melancholia, and the …

The hormone ghrelin stimulates eating and helps maintain blood glucose upon caloric
restriction. While previous studies have demonstrated that hypothalamic arcuate AgRP …

Recent studies have suggested that mitochondrial dysfunction and dysregulated
neuroinflammatory pathways are involved in the pathophysiology of major depressive …

Several psychiatric disorders increase the risk of cardiovascular disease, including
posttraumatic stress disorder and major depression. While the precise mechanism for this …

The purpose of this study was to determine whether aspirin (A) ingestion combined with
prolonged exercise increases gastrointestinal permeability and whether consumption of a …

Objective: Microbiota dysbiosis has been linked to major depressive disorder, but the
mechanisms whereby the microbiota modulates mood remain poorly understood. The …

Introduction Characterise gut microbiota distributions of participants with co-occurring
depression and anxiety, in those with only depression or with anxiety, and determine if gut …

Thirteen lots of plasma protein fraction made by one manufacturer were implicated in 23
recent reports of hypotension in surgical patients. Four of these patients required …