Benzene and leukemia

RA Rinsky, AB Smith, R Hornung… - New England journal …, 1987 - Mass Medical Soc
To assess quantitatively the association between benzene exposure and leukemia, we
examined the mortality rate of a cohort with occupational exposure to benzene. Cumulative …

Enterococci enhance Clostridioides difficile pathogenesis

AB Smith, ML Jenior, O Keenan, JL Hart, J Specker… - Nature, 2022 - nature.com
Enteric pathogens are exposed to a dynamic polymicrobial environment in the
gastrointestinal tract. This microbial community has been shown to be important during …

Leukemia in benzene workers

RA Rinsky, RJ Young, AB Smith - American Journal of …, 1981 - Wiley Online Library
To evaluate the possible association between occupational exposure to benzene and
subsequent death from leukemia, the National Institute for Occupational Safety and Health …

Mortality among workers exposed to polychlorinated biphenyls

T Sinks, G Steele, AB Smith, K Watkins… - American journal of …, 1992 - academic.oup.com
On the basis of evidence from animal studies, polychlotinated biphenyls (PCBs) are
considered potentially carcinogenic to humans. However, the results of studies in human …

Renal toxicity in uranium mill workers

MJ Thun, DB Baker, K Steenland, AB Smith… - Scandinavian journal of …, 1985 - JSTOR
Although the kidney is the critical organ limiting occupational exposure to soluble uranium
compounds, there have been no adequate studies evaluating renal tubular dysfunction in …

Discovery of CDZ173 (Leniolisib), representing a structurally novel class of PI3K delta-selective inhibitors

K Hoegenauer, N Soldermann, F Zecri… - ACS medicinal …, 2017 - ACS Publications
The predominant expression of phosphoinositide 3-kinase δ (PI3Kδ) in leukocytes and its
critical role in B and T cell functions led to the hypothesis that selective inhibitors of this …

Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB …

GJ MacDonald, CL Branch, MS Hadley… - Journal of medicinal …, 2003 - ACS Publications
At their clinical doses, current antipsychotic agents share the property of both dopamine D2
and D3 receptor blockade. However, a major disadvantage of many current medications are …

Half-life of polychlorinated biphenyls in occupationally exposed workers

DL Phillips, AB Smith, VW Burse… - Archives of …, 1989 - Taylor & Francis
In 1977 and 1985, serum polychlorinated biphenyl (PCB) concentrations were determined
for 58 workers in a Bloomington, Indiana, factory that used polychlorinated biphenyls (PCBs) …

Authoritarianism in policemen who are college graduates and non-college police

AB Smith, B Locke, A Fenster - The Journal of Criminal Law, Criminology …, 1970 - JSTOR
This is the last of three articles dealing with the impact of college education on New York
City police. In 1967 Smith, Locke, and Walker published an article in this Journal comparing …

Discovery and pharmacological characterization of novel quinazoline-based PI3K delta-selective inhibitors

K Hoegenauer, N Soldermann, F Stauffer… - ACS Medicinal …, 2016 - ACS Publications
Inhibition of the lipid kinase PI3Kδ is a promising principle to treat B and T cell driven
inflammatory diseases. Using a scaffold deconstruction–reconstruction strategy, we …