Elsevier

Preventive Medicine

Volume 54, Supplement, 1 May 2012, Pages S38-S41
Preventive Medicine

Review
A global view on the development of non communicable diseases

https://doi.org/10.1016/j.ypmed.2011.11.012Get rights and content

Abstract

For a long time non communicable diseases (NCDs) were discussed as burden of the developed world. Recent alarming data show a reverse trend and a dramatic increase of NCDs in the developing world, in particular in highly populated transition countries. This is true for the main mortality triggering diseases such as CVD, cancer or diabetes. Almost 4 out of 5 NCD based deaths happen in low- and middle income countries. This development is multi-factorial and is based on some main trends such as globalization, supermarket growth, rapid urbanization and increasingly sedentary lifestyles. The latter leads to overweight or obesity, which again promotes NCDs similar as high blood pressure, high cholesterol and elevated blood glucose.

A high quality diet including functional food or functional ingredients, accompanied by physical activity and a non-smoking policy, is one of the most promising factors in primary and secondary prevention of NCDs.

Highlights

► Nearly 80% of NCD deaths occur in low-and middle-income countries. ► Main risk factors for NCDs are tobacco use, unhealthy diet, physical inactivity and alcohol. ► More than 1.3 billion people globally are overweight or obese. ► Responsible are globalization, rapid urbanization and increasingly sedentary life styles.

Introduction

Of the 57 million global deaths in 2008, 63% or 36 million were due to non communicable diseases (NCDs) (Alwan et al., 2010) and annual NCD deaths are projected to further rise worldwide. NCDs which mainly comprise cardiovascular diseases (CVD), diabetes, cancers and chronic respiratory diseases were few decades ago, as popular believe presumes, typically found in developed countries due to the predominantly sedentary lifestyle (WHO, 2010a, WHO, 2010b).

However, the greatest increase is expected to be seen in highly populated low- and middle-income regions. Nearly 80% of NCD deaths occur in low- and middle-income countries and NCDs are the most frequent causes of death in most countries in the Americas, the Eastern Mediterranean, Europe, South-East Asia, and the Western Pacific, except in Africa. Even in African nations, NCDs are rising rapidly and are projected to exceed communicable, maternal, perinatal, and nutritional diseases as the most common causes of death by 2030 (WHO, 2008, WHO, 2010a, WHO, 2010b).

NCDs also lead to death at a younger age in low- and middle-income countries, where 29% of NCD deaths occur among people under the age of 60, compared to 13% in high-income countries. For cancer incidence, the estimated percentage increase by 2030, compared with 2008, will be greater in low- (82%) and lower-middle-income countries (70%) compared with the upper-middle- (58%) and high-income countries (40%) (Farmer et al., 2010, Ferlay et al., 2010, WHO, 2010a, WHO, 2010b). The same tendency is true for CVD and type 2 diabetes.

Section snippets

Risk factors for the NCDs

The main risk factors for NCDs for individuals are well known for decades and are similar in almost all countries. Tobacco use, unhealthy diet with foods high in saturated and trans fats, salt and sugar (especially in sweetened drinks), physical inactivity and the harmful consumption of alcohol cause more than two-thirds of all new cases of NCDs and increase the risk of complications in people with NCDs. At least 80% of heart disease, stroke and type 2 diabetes, as well as 40% of cancer could

Global developments of NCDs

In 2008, the overall NCD age-standardized death rates in low- and middle-income countries were 756 per 100,000 for males and 565 per 100,000 for females — respectively 65% and 85% higher than for men and women in high-income countries. Age-standardized NCD mortality rates for all ages were highest in the African Region for males (844 per 100,000) and for females (724 per 100,000). The leading causes of NCD deaths in 2008 were: cardiovascular diseases (17 million deaths, or 48% of NCD deaths);

Some explanations for this global development

The rapidly growing burden of NCDs in low- and middle-income countries seems to be mainly due to the negative effects of globalization, rapid urbanization and increasingly sedentary lifestyles. These countries are in various phases of the epidemiologic transition. As countries progress from agrarian to industrial to postindustrial states, there are a series of environmental, social, and structural changes that occur, some that lead to increase longevity, others that result in exposure to risk

Conclusion

NCDs represent a significant and unfortunately growing burden worldwide. During decades they were mainly a topic of developed countries, nowadays they represent the main problem of the developing world. These trends reflect the growing societies, rapid unplanned urbanization and increasingly sedentary lives. Currently, the main focus of health care for NCDs in many low- and middle-income countries is hospital centered acute care. To ensure early detection and timely treatment, NCDs need to be

Conflict of interest statement

No conflict of interest.

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