Table 1

Comparative characteristics of patients in derivation and validation cohorts

	Cohort, no (%) of patients
	Total (n=996)		Derivation (n=664)		Validation (n=332)		P value
Demographics and clinical characteristics
Age (years), mean (SD)	87.0	0.2	87.0	0.3	87.2	0.4	0.513
Sex
Women, %	589	59.1	394	59.3	195	58.7	0.856
Nursing home, %	191	19.2	125	18.8	66	19.9	0.691
Advanced malignancy, %	45	4.5	27	4.1	18	5.4	0.332
Chronic kidney disease, %	166	16.7	115	17.3	51	15.4	0.232
Chronic heart failure, %	233	23.4	168	25.3	65	19.6	0.030*
Chronic obstructive pulmonary disease, %	124	12.4	79	11.9	45	13.6	0.456
Cerebrovascular disease, %	25	2.5	18	2.7	7	2.1	0.674
Myocardial infarction, %	255	25.6	167	25.2	88	26.5	0.645
Moderate/severe liver disease, %	71	7.1	40	6.0	31	9.3	0.048*
Cognitive impairment, %	255	25.6	172	25.9	83	25.0	0.758
ADL score, median (IQR)	4.5	3–5.5	4.5	3–5.5	4.5	2.5–5.5	0.490
Weight (kg), mean (SD)	67.1	0.5	66.7	0.6	67.8	0.9	0.286