Technique for CDSUD
| PCU (n=11) | PCST (n=11) | Total (n=22) | P value | |
| Drugs used | ||||
| Dual therapy (midazolam+other drug) | 7 (64) | 4 (36) | 11 (50) | |
| Midazolam | 11 (100) | 11 (100) | 22 (100) | |
| Levomepromazine | 3 (27) | 0 | 3 (14) | |
| Hydroxyzine | 3 (27) | 0 | 3 (14) | |
| Diazepam | 0 | 2 (18) | 2 (9) | |
| Cyamemazine | 0 | 1 (9) | 1 (4) | |
| Dipotassium clorazepate | 1 (9) | 0 | 1 (4) | |
| Loxapine | 0 | 1 (9) | 1 (4) | |
| Dosage of midazolam (in mg/24 hours) | ||||
| Mean | 83 (15–132) | 147 (17–480) | 115 (15–480) | 0.21 |
| Initial | 39 (5–100) | 132 (17–480) | 85 (5–480) | 0.01 |
| Final | 117 (20–288) | 165 (17–480) | 152 (17–480) | 0.92 |
| Tachyphylaxis | 8 (73) | 5 (46) | 13 (59) | |
| Duration in days (mean, minimum, maximum) | 3.2 (1–7) | 2.5 (0.02–14) | 3 (0.02–14) | 0.15 |
| Proportional sedation until death | 6 (54) | 1 (9) | 7 (17) | 0.07 |
CDSUD, continuous deep sedation until death; PCST, palliative care support team; PCU, palliative care unit.