Emesis end points during cycle 1 of AC in the acute (0–24 hours), delay (24–120 hours) and overall phases (0–120 hours)
| Acute (0–24 hours), n (%) | Delay (24–120 hours), n (%) | Overall (0–120 hours), n (%) | ||||
| NEPA | Historical controls (APR) | NEPA | Historical controls (APR) | NEPA | Historical controls (APR) | |
| No vomiting | 43 (71.7) | 44 (72.1) | 37 (86.0) | 34 (75.6) | 37 (61.7) | 34 (54.8) |
| No use of rescue therapy | 51 (85.0) | 60 (98.4) | 46 (90.2) | 51 (83.6) | 46 (76.7) | 51 (82.3) |
| No significant nausea | 52 (86.7) | 54 (88.5) | 47 (90.4) | 40 (74.1) | 47 (78.3) | 41 (66.1) |
| No nausea | 42 (70.0) | 38 (62.3) | 32 (76.2) | 18 (47.3) | 32 (53.3) | 19 (30.6) |
| Complete response | 42 (70.0) | 44 (72.1) | 36 (85.7) | 29 (64.4) | 36 (60.0) | 29 (46.8) |
| Complete protection | 40 (66.7) | 41 (67.2) | 34 (85.0) | 23 (56.1) | 34 (56.7) | 24 (38.7) |
| Total control | 38 (63.3) | 33 (54.1) | 29 (76.3) | 15 (45.5) | 29 (48.3) | 16 (25.8) |