Analysis of the G-CSF preference for primary and secondary prophylaxis according to healthcare sector in which the physicians work
G-CSF attribute | Primary prophylaxis preference | Secondary prophylaxis preference (exploratory analysis) | ||||||
Public sector (n=150) | Private sector (exclusively or with public sector) (n=55) | Public sector (n=150) | Private sector (exclusively or with public sector) (n=55) | |||||
Coefficient | P value | Coefficient | P value | Coefficient | P value | Coefficient | P value | |
Efficacy | ||||||||
Risk of febrile neutropenia with prophylaxis | 0.038 | 0.042 | ||||||
G-CSF characteristic | ||||||||
Biosimilar | 0.148 | <0.001 | 0.135 | <0.001 | 0.121 | <0.001 | ||
G-CSF administration and cost | ||||||||
Cost per injection, including cost of nurse (euros) | 0.11× | <0.001 | 0.125 | <0.001 | 0.098 | <0.001 | 0.114 | <0.001 |
Number of injections per chemotherapy cycle | 0.213 | <0.001 | 0.208 | <0.001 | 0.147 | <0.001 | 0.096 | <0.001 |
Tolerance | ||||||||
Pain at the injection site | 0.072 | <0.001 | 0.091 | 0.004 | 0.082 | 0.012 | ||
Bone pain present | −0.04 | 0.034 | −0.072 | <0.001 | −0.073 | 0.025 | ||
Fever/influenza syndrome present | −0.04× | 0.041 | −0.082 | 0.012 |
G-CSF, granulocyte colony-stimulating factors.