Characteristic | No of participants (n = 100) |
Age | |
Median (range) | 63 years (35–86 years) |
Gender | |
Female | 47 |
Male | 53 |
Cancer primary location | |
Breast | 12 |
Endocrine | 4 |
Gastrointestinal | 24 |
Gynaecological | 5 |
Haematological | 7 |
Head and neck | 8 |
Lung | 16 |
Neurological | 1 |
Sarcoma | 3 |
Skin | 1 |
Urological | 17 |
Other | 2 |
ECOG performance status | |
0 | 3 |
1 | 41 |
2 | 33 |
3 | 22 |
4 | 1 |
Opioid analgesic at baseline (regular prescription)* | |
Alfentanil | 1 |
Buprenorphine | 8 |
Codeine | 19 |
Fentanyl | 15 |
Morphine | 50 |
Oxycodone | 15 |
Tramadol | 2 |
Laxative and related products at baseline (regular prescription)† | |
None | 28 |
Osmotic laxatives | 36 |
Lactulose | 4 |
Macrogol | 32 |
Softening laxatives | 30 |
Docusate sodium | 30 |
Stimulant laxatives | 42 |
Bisacodyl | 7 |
Senna | 35 |
Peripherally acting mu-opioid receptor antagonists | 5 |
Naloxegol | 5 |
*Ten patients using two opioid analgesics.
†Twenty-six patients using two products; eight patients using three products.
ECOG, Eastern Co-operative Oncology Group.