ALSFRS-R scores stratified by disease burden
ALSFRS-R and components | ALSFRS-R score | Disease burden | |||
Mild Disease subjects=20 mean±SD | Intermediate Spinal subjects=8 mean±SD | Intermediate Bulbar subjects=4 mean±SD | Severe Disease subjects=12 mean±SD | ||
ALSFRS-R | ≤48 | 34.1±11.8 | 36.0±7.4 | 20.5±4.0 | 15.3±9.6 |
Bulbar component | ≤12 | 10.1±2.3 | 11.0±2.4 | 7.0±2.3 | 3.7±4.3 |
Motor component | ≤24 | 14.2±8.1 | 13.6±5.2 | 5.0±4.6 | 4.7±5.2 |
Fine motor score | ≤16 | 9.5±6.2 | 9.5±4.3 | 3.5±2.9 | 3.4±4.1 |
Gross motor score | ≤12 | 7.4±3.5 | 6.5±2.8 | 2.0±2.3 | 2.0±2.9 |
Respiratory component | ≤12 | 9.9±3.2 | 11.4±1.2 | 8.5±1.7 | 7.0±3.0 |
ALSFRS-R, Revised Amyotrophic Lateral Sclerosis Functional Rating Scale.