Table 2

ALSFRS-R scores stratified by disease burden

ALSFRS-R and componentsALSFRS-R scoreDisease burden
Mild Disease
subjects=20
mean±SD
Intermediate Spinal
subjects=8
mean±SD
Intermediate Bulbar
subjects=4
mean±SD
Severe Disease
subjects=12
mean±SD
ALSFRS-R≤4834.1±11.836.0±7.420.5±4.015.3±9.6
Bulbar component≤1210.1±2.311.0±2.47.0±2.33.7±4.3
Motor component≤2414.2±8.113.6±5.25.0±4.64.7±5.2
Fine motor score≤169.5±6.29.5±4.33.5±2.93.4±4.1
Gross motor score≤127.4±3.56.5±2.82.0±2.32.0±2.9
Respiratory component≤129.9±3.211.4±1.28.5±1.77.0±3.0
  • ALSFRS-R, Revised Amyotrophic Lateral Sclerosis Functional Rating Scale.