Severity | P value | |||||
Status | Mild Disease (subjects=20) | Intermediate Spinal (subjects=8) | Intermediate Bulbar (subjects=4) | Severe Disease (subjects=12) | Total (subjects=44) | |
Carers (N=33) | 205 (138 to 375); carers=12 | 378 (347 to 993); carers=5 | 1262 (574 to 1493); carers=4 | 624 (202 to 1575); carers=12 | 375 (247 to 993); carers=33 | 0.052* 0.015† |
Patients (N=11) | 517 (154 to 1178); patients=8 | 1099 (82 to 1825); patients=3 | – | – | 551 (154 to 1178); patients=11 | 0.838‡ |
Total | 275 (160 to 551) | 460 (316 to 1099) | – | – | ||
P (Mann-Whitney) | 0.123§ | 0.456§ | – | – | ||
P (ANOVA by bootstrapping) | 0.141 (status); 0.128 (disease burden); 0.890 (interaction) |
*Kruskal-Wallis test, univariate, comparing severity within status.
†Jonckheere-Terpstra test, univariate, comparing severity within status, on the assumption of ordered response.
‡Mann-Whitney U test, univariate, comparing severity within status.
§Mann-Whitney U test, univariate, comparing status within severity.
ANOVA, analysis of variance.