Domperidone orodispersible
| Domperidone orodispersible | |
| What is it? | Antiemetic |
| Mechanism of action | Prokinetic D2 antagonist |
| Starting dose | 10 mg prn three times a day |
| Time to onset of effect | 30 min(17) |
| Formulation | 10 mg orodispersible tablets |
| Indication | Nausea and vomiting |
| Common adverse effects | Dry mouth; anxiety; asthenia; breast abnormalities; diarrhoea; drowsiness; headache; lactation disorders16 |
| Contraindications | QT abnormality Prolactinoma16 |
| Caution | Patients >60 |
| Licence | Orodisperible tablet unlicensed product |
| Benefits | Alternative route of administration |
| Risks | Extrapyramidal adverse effects |
| Cost | Orodispersible tablet—special price of application |