Table 14

Hyoscine hydrobromide chewable

Hyoscine hydrobromide chewable
What is it?Antimuscarinic
Mechanism of actionAntisecretory with smooth muscle relaxant properties
Starting dose150 μg 4 hourly prn
Time to onset of effect10–15 min17
FormulationChewable tablets
Smooth muscle spasm
Paraneoplastic fevers and sweating
Common Adverse EffectsConstipation; dizziness; drowsiness; dry mouth; dyspepsia; flushing; headache; nausea; palpitations; skin reactions; tachycardia; urinary disorders; vision disorders; vomiting16
ContraindicationsTachycardia >100
Cardiac conduction disorders16
CautionCrosses blood brain barrier so may cause sedation
Renal and hepatic impairment
May prefer to use transdermal patch
Licence‘off label’ use of a licensed product
BenefitsChewable alternative
Cost£1.67 for 12×150 mg Kwells
£1.99 for 12×150 μg Joy-Rides tablet