Variables | Total no of patients | Home death | Univariate | Cardiopulmonary resuscitation† | Univariate | Intubation and mechanical ventilation support† | Univariate |
n (%) | OR (95% CI) | n (%) | OR (95% CI) | n (%) | OR (95% CI) | ||
Advance care planning | |||||||
No | 1709 | 68 (3.98) | 1 | 138 (8.07) | 1 | 303 (17.73) | 1 |
Yes | 1487 | 98 (6.59) | 1.70 (1.24 to 2.34)*** | 45 (3.03) | 0.36 (0.25 to 0.50)*** | 154 (10.36) | 0.54 (0.44 to 0.66)*** |
Age, years | |||||||
18–64 | 614 | 22 (3.58) | 1 | 52 (8.47) | 1 | 114 (18.57) | 1 |
≥65 | 2582 | 144 (5.58) | 1.59 (1.01 to 2.51)* | 131 (5.07) | 0.58 (0.41 to 0.81)** | 343 (13.28) | 0.67 (0.53 to 0.85)*** |
Sex | |||||||
Female | 1377 | 96 (6.97) | 1 | 70 (5.08) | 1 | 169 (12.27) | 1 |
Male | 1819 | 70 (3.85) | 0.53 (0.39 to 0.73)*** | 113 (6.21) | 1.24 (0.91 to 1.68) | 288 (15.83) | 1.35 (1.10 to 1.65)** |
Palliative Care Screening Score | |||||||
<4 points | 1672 | 90 (5.38) | 1 | 110 (6.58) | 1 | 287 (17.17) | 1 |
≥4 points | 1524 | 76 (4.99) | 0.92 (0.67 to 1.26) | 73 (4.79) | 0.71 (0.53 to 0.97)* | 170 (11.15) | 0.61 (0.49 to 0.74)*** |
ECOG performance status | |||||||
Grade 0 | 323 | 16 (4.95) | 1 | 22 (6.81) | 1 | 61 (18.89) | 1 |
Grade 1 | 375 | 30 (8.00) | 1.69 (0.89 to 3.12) | 27 (7.20) | 1.06 (0.59 to 1.90) | 73 (19.47) | 1.04 (0.71 to 1.52) |
Grade 2 | 346 | 22 (6.36) | 1.30 (0.67 to 2.53) | 24 (6.94) | 1.02 (0.56 to 1.86) | 58 (16.76) | 0.87 (0.58 to 1.29) |
Grade 3 | 709 | 37 (5.22) | 1.06 (0.58 to 1.93) | 40 (5.64) | 0.82 (0.48 to 1.40) | 104 (14.67) | 0.74 (0.52 to 1.05) |
Grade 4 | 1443 | 61 (4.23) | 0.85 (0.48 to 1.49) | 70 (4.85) | 0.70 (0.43 to 1.14) | 161 (11.16) | 0.54 (0.39 to 0.75)*** |
Heart failure | |||||||
None | 2885 | 150 (5.20) | 1 | 162 (5.62) | 1 | 403 (13.97) | 1 |
Mild | 85 | 5 (5.88) | 1.14 (0.46 to 2.86) | 6 (7.06) | 1.28 (0.55 to 2.97) | 19 (22.35) | 1.77 (1.05 to 2.99)* |
Moderate | 113 | 6 (5.31) | 1.02 (0.44 to 2.37) | 9 (7.96) | 1.46 (0.72 to 2.93) | 24 (21.24) | 1.66 (1.05 to 2.64)* |
Severe | 113 | 5 (4.42) | 0.84 (0.34 to 2.10) | 6 (5.31) | 0.94 (0.41 to 2.18) | 11 (9.73) | 0.66 (0.35 to 1.25) |
Other comorbidities | |||||||
Cancer | 750 | 58 (7.73) | 1.81 (1.30 to 2.52)*** | 13 (1.73) | 0.24 (0.13 to 0.42)*** | 33 (4.40) | 0.22 (0.15 to 0.32)*** |
Liver cirrhosis | 177 | 13 (7.34) | 1.49 (0.83 to 2.67) | 8 (4.52) | 0.77 (0.37 to 1.59) | 24 (13.56) | 0.94 (0.60 to 1.46) |
End-stage renal disease | 170 | 12 (7.06) | (0.77 to 2.60) | 18 (10.59) | 2.05 (1.23 to 3.43)** | 33 (19.41) | 1.48 (1.00 to 2.19) |
Dementia | 46 | 3 (6.52) | 1.28 (0.39 to 4.17) | 3 (6.52) | 1.15 (0.35 to 3.74) | 4 (8.70) | 0.58 (0.20 to 1.59) |
Frequency of underlying disease exacerbations | |||||||
Visited emergency department more than once in the last 30 days | 119 | 7 (5.88) | 1.15 (0.53 to 2.50) | 4 (3.36) | 0.56 (0.21 to 1.54) | 8 (6.72) | 0.42 (0.20 to 0.87)* |
Hospitalised more than once in the last 30 days | 70 | 3 (4.29) | 0.81 (0.25 to 2.62) | 2 (2.86) | 0.48 (0.12 to 1.97) | 5 (7.14) | 0.46 (0.18 to 1.14) |
*P<0.05; **P<0.01; ***P<0.001.
†During the last 3 months of life.
ECOG, Eastern Cooperative Oncology Group.