Table 1

Eligibility criteria for inclusion of studies

PICOS factorsInclusion criteriaExclusion criteria
PopulationPatients with any type of cancer, including haematological and solid tumoursPatients undergoing surgery, cannabis taken recreationally and cannabis in addiction, animal studies
InterventionMultiple doses of cannabinoids via any route, for pain cancer-related management (studies where only the minority of the exposed group received cannabis and cannabinoids were excluded)Single-dose studies
Comparison/controlAny type of comparator, including placeboNo comparator/control group
OutcomePain as the primary outcomePain not the primary outcome
Study designRandomised controlled trialsCohort studies, prospective and retrospective observational studies, case studies and database analysis