Eligibility criteria for inclusion of studies
| PICOS factors | Inclusion criteria | Exclusion criteria |
| Population | Patients with any type of cancer, including haematological and solid tumours | Patients undergoing surgery, cannabis taken recreationally and cannabis in addiction, animal studies |
| Intervention | Multiple doses of cannabinoids via any route, for pain cancer-related management (studies where only the minority of the exposed group received cannabis and cannabinoids were excluded) | Single-dose studies |
| Comparison/control | Any type of comparator, including placebo | No comparator/control group |
| Outcome | Pain as the primary outcome | Pain not the primary outcome |
| Study design | Randomised controlled trials | Cohort studies, prospective and retrospective observational studies, case studies and database analysis |