Table 1

Baseline characteristics of studied populations (n=122)

NEPA, N (%)Historical controls (APR), N (%)
Median age (years; range)56 (30–69)46.5 (32–66)
Median body weight (kg; range)55.6 (38.9–87.9)57.8 (40.8–97.2)
Median body height (cm; range)157 (146–170)159 (147–171)
Median body surface area
(m2; range)
1.56 (1.31–1.94)
Primary tumour pathology
 Ductal55 (91.7)59 (95.2)
 Lobular3 (5.0)1 (1.6)
 Other2 (3.3)2 (3.2)
Stage of cancer
 I3 (5.0)18 (29.0)
 II40 (66.7)28 (45.2)
 III17 (28.3)16 (25.8)
History of motion sickness21 (35.0)14 (22.6)
History of vomiting during pregnancy
 Yes24 (40.0)22 (35.5)
 Never pregnant4 (6.7)12 (19.4)
Regular alcoholic drink2 (3.3)1 (1.6)
AC regimen
 3-week cycle45 (75.0)62 (100)
 2-week cycle15 (25.0)0
AC treatment setting
 Neoadjuvant18 (30.0)0
 Adjuvant42 (70.0)62 (100)