Table 1

General characteristics of cancer randomised controlled trials including elderly patients

VariableCategoryTotal (n=72)
International (if more than one country)No48 (66.7)
Yes24 (33.3)
Industry supported (fully or in part)No35 (48.6)
Yes37 (51.4)
Disease stageOnly metastatic/advanced35 (48.6)
Only non-metastatic/local27 (37.5)
Both8 (11.1)
Unclear2 (2.8)
Overall study sample size≤20033 (45.8)
>20039 (54.2)
Secondary paper on PRONo51 (70.8)
Yes21 (29.2)
Year of publication2004–201037 (51.4)
2011–201935 (48.6)
Type of treatment used*Radiotherapy11 (15.3)
Surgery8 (11.1)
Chemotherapy26 (36.1)
Targeted therapy9 (12.5)
Hormonal therapy26 (36.1)
Other14 (19.4)
PRO endpointPrimary20 (27.8)
Secondary52 (72.2)
  • *More than one option could be chosen.

  • PRO, patient-reported outcome.