Table 1

Reports of studies on chemotherapy during the last 30 days of life (DOL)

% Receiving chemotherapy during
Study Patients, N Type of cancer Inclusion criteria Last 30 DOL Last 14 DOL
Rautakorpi et al 25 38 982AllAny167.2
Falchook et al 32 12 765LungPatients<65 years12.6
Ersek et al 42 847NSCLCAny30.6
Wright et al 14 1146AllAny6.5
Bekelman et al 49 389 073AllUSA10.6
The Netherlands10.6
Belgium12.7
Canada8.8
UKNR
Germany10.5
Norway4.8
Sano and Fushimi45 26 012AllPalliative care consultation1.7
SOC4.0
Parekh et al 51 242NSCLC2009–10 Prepalliative care17.0
2003–14 Postpalliative care7.0
Pacetti et al 39 2164AllAny24.3
Wang et al 52 82 242All20054.4
20094.0
Choi et al 30 263All200214.03.5
201242.723.8
Cheung et al 31 107 253AllAny3.6
Lee et al 38 2345All200025.7
200532.7
201044.2
Kok et al 27 266NSCLC2008–20095.0
2011–20121.0
Zhang et al 63 118NSCLCAny27
Adam et al 33 120AllAny11.77.6
Sesé et al 35 94LungAny5522
Amano et al 58 266AllEarly palliative care17
SOC23
Greer et al 29 151NSCLCSOC43.323.9
Early palliative care30.013.6
Mack et al 46 1231NSCLC and colorectalAny16.0
Näppä et al 40 374AllAny23
Gonsalves et al 44 200All20025
200818
Ho et al 37 227 161All19932.02
20032.9
Andreis et al 59 102AllAny166
Warren et al 53 21 633AllPatients with OS <6 months14.89
Patients with OS >6 months10.26.4
Keating et al 47 5826NSCLC and colorectalVHA cohort4.6
SEER cohort7.5
Kao et al 62 747AllAny188.0
Hashimoto et al 55 255AllAny12.63.10
Tang et al 28 242 530AllTrend 2000–200616.2
Barbera et al 34 5855AllAny4.6
Earle et al 11 215 484All19939.70
199911.6
Temel et al 36 46NSCLCIntegrated palliative care4023
Yun et al 54 3750AllAny30.922.5
Murillo and Koeller41 417NSCLCAny4320.0
Earle et al 16 28 777All199313.8
199618.5
Giorgi et al 57 193AllAny33
Emanuel et al 48 7919AllMassachusetts9
California9
Aragon-Ching et al 56 144AllAny26
  • NR, not reported; NSCLC, non-small cell lung cancer; SEER, Surveillance, Epidemiology and End Results; SOC, standard of care; VHA, Veterans Health Administration.