Actigraphy data
| CRFS cases | Controls | ||||
|---|---|---|---|---|---|
| Variable | Mean | SD | Mean | SD | p Value |
| Sleep | |||||
| Actual sleep time (h) | 06:04 | 00:44:41 | 06:07 | 00:45:56 | 0.74 |
| Actual sleep (%) | 84.40 | 6.41 | 82.49 | 10.28 | 0.27 |
| Actual wake time (h) | 01:07 | 00:28:29 | 01:11 | 00:30:31 | 0.48 |
| Actual wake (%) | 17.51 | 10.27 | 15.60 | 6.41 | 0.28 |
| Sleep efficiency (%) | 80.22 | 7.73 | 78.44 | 13.28 | 0.43 |
| Sleep latency (min) | 00:17:32 | 00:20:27 | 00:17:19 | 00:27:36 | 0.97 |
| Average number of calculated sleep bouts | 23.73 | 6.60 | 24.04 | 7.02 | 0.82 |
| Average number of calculated wake bouts | 23.77 | 6.68 | 24.10 | 7.02 | 0.81 |
| Mean sleep bout time (min) | 00:33:03 | 00:44:41 | 00:19:20 | 00:13:41 | 0.02 |
| Activity | |||||
| Mean wake bout time (min) | 00:02:43 | 00:00:42 | 00:03:25 | 00:00:28 | 0.19 |
| Average value of epoch intensity (24 h period) | 208.48 | 87.22 | 245.82 | 96.32 | 0.04 |
| Difference in maximum and minimum activity | 198.85 | 69.70 | 218.55 | 88.97 | 0.45 |
| Peak intensity of epoch | 11.91 | 5.02 | 11.99 | 4.68 | 0.22 |
| Average of daytime (light) activity | 299.25 | 131.18 | 342.92 | 119.92 | 0.03 |
| Time of night time (dark) activity | 117.70 | 55.24 | 148.72 | 90.60 | 0.14 |
| Ratio of light to dark activity | 2.99 | 1.54 | 2.99 | 1.54 | 0.82 |
| Circadian rhythm | |||||
| Interdaily stability | 0.53 | 0.12 | 0.57 | 0.15 | 0.16 |
| Interdaily variability | 0.86 | 0.21 | 0.83 | 0.21 | 0.14 |
| Least 5 (L5) active hours | 1475 | 1010 | 2348 | 1634 | 0.50 |
| Most 10 (M10) active hours | 22481 | 7774 | 24865 | 8722 | 0.50 |
| Relative amplitude | 0.88 | 0.07 | 0.86 | 0.14 | 0.22 |
Sleep efficiency (%) is time asleep (as per algorithm) divided by total time in bed.
Sleep latency is time in bed before algorithm records the subject being asleep.
Average value of epoch intensity (24 h period): the recording is converted to and analysed as a cosine wave around a zero point.
Difference in maximum and minimum in activity corresponds to the difference between the peak and trough of the cosine wave.
Interdaily stability is a measure of consistency in daily activity over 7 days.
Interdaily variability is a measure of fragmentation of periods of rest and activity; normal value are <1 and calculated over 7 days.
L5 indicates the 5 h of calculated lowest activity over the 7-day average.
M10 indicates the 10 h of calculated greatest activity over the 7-day average.
Relative amplitude is a measure of the difference between L5 and M10 and thus an indication of overall level of activity over the 7-day period.
CRFS, cancer-related fatigue syndrome.