Patient demographics for each ADO (for ‘Age, Dyspnoea and airflow Obstruction’) score category, with SD given for continuous variables, and comparing the groups’ mean values using one-way analysis of variance (ANOVA), where p<0.05 is deemed statistically significant
| Demographic | ADO score 2 and 3 (n=28) (±SD) | ADO score 4 and 5 (n=26) (±SD) | ADO score≥6 (n=41) (±SD) | Group comparisons: p value for one-way ANOVA |
|---|---|---|---|---|
| Male | 15 (53.6%) | 9 (34.6%) | 14 (34.1%) | – |
| Female | 13 (46.4%) | 17 (65.3%) | 27 (65.9%) | – |
| Mean age, years | 69 (±5.71) | 76 (±7.92) | 71 (±9.13) | p=0.0033* |
| Mean FEV1% predicted | 0.48 (±0.19) | 0.61 (±0.25) | 0.43 (±0.17) | p=0.0012* |
| Mean BMI | 26 (±7.46) | 24 (±6.90) | 27 (±7.47) | p=0.5960 |
| Mean MRC grade | 4 | 4 | 4 | p=0.0541 |
| Mean gas transfer (DLCO% predicted) | 0.45 (±0.15) | 0.50 (±0.15) | 0.35 (±0.14) | p=0.0445* |
*Statistically significant p value.
ANOVA, analysis of variance; BMI, body mass index; DLCO%, diffusion capacity of the lung for carbon monoxide; FEV1, forced expiratory volume in 1 s; MRC, Medical Research Council.