Table 2

HR for ADO (for ‘Age, Dyspnoea and airflow Obstruction’) score alongside each of the variables

CovariateADO HR (CI), p valueCovariate HR (CI), p value
None1.26 (1.09 to 1.46), p=0.001*–
Age1.26 (1.09 to 1.45), p=0.002*1.02 (0.99 to 1.05), p=0.33
FEV11.25 (1.08 to 1.44), p=0.002*0.52 (0.14 to 1.93), p=0.33
MRC1.21 (1.05 to 1.40), p=0.01*1.28 (0.95 to 1.74), p=0.106
BMI1.22 (1.04 to 1.43), p=0.015*0.95 (0.90 to 0.99), p=0.027*
DLCO1.53 (1.16 to 2.01), p=0.003*0.135 (0.01 to 3.34), p=0.221
Sex1.26 (1.09 to 1.46), p=0.002*1.03 (0.60 to 1.78), p=0.911

  • The results indicate an increase in ADO remains independently associated with shorter survival after adjusting for other factors. BMI was independently and significantly associated with outcome (higher BMI was associated with better outcome).

  • *Statistically significant p value.

  • BMI, body mass index; DLCO, diffusion capacity of the lung for carbon monoxide; FEV1, forced expiratory volume in 1 s; MRC, Medical Research Council.