PT - JOURNAL ARTICLE AU - Mendes, M Aurora AU - Muijsenberg, Anouk JL AU - Houben-Wilke, Sarah AU - Houben, Carmen HM AU - Spruit, Martijn A AU - Marques, Alda AU - Janssen, Daisy J A TI - End-of-life preferences of people with advanced chronic obstructive pulmonary disease AID - 10.1136/spcare-2024-005067 DP - 2024 Sep 19 TA - BMJ Supportive & Palliative Care PG - spcare-2024-005067 4099 - http://spcare.bmj.com/content/early/2024/09/19/spcare-2024-005067.short 4100 - http://spcare.bmj.com/content/early/2024/09/19/spcare-2024-005067.full AB - Objectives To identify end-of-life preferences of people with advanced chronic obstructive pulmonary disease (COPD) and to compare characteristics between those who wish to discuss the end-of-life and those who do not.Methods An analysis of the baseline data of a randomised controlled trial was performed including people with COPD GOLD stages III–IV or former quadrant D with modified Medical Research Council questionnaire grade ≥2, after hospital discharge following an exacerbation. Participants were interviewed using the End-of-Life Preferences Interview.Results A total of 165 individuals (53% men; 68±9 years old; 55% care dependent) were included. Most participants wished to take part in shared decision-making (78%), to be informed about a short life expectancy (82%), to discuss the end-of-life (82%), to have loved ones around at death (87%) and to choose when to die (70%). They also reported accepting opioids (74%). Preferences for who to provide physical care, the place, consciousness and atmosphere at death as well as life-sustaining treatments were heterogeneous. Participants who wanted to discuss the end-of-life had a significantly higher educational level (p=0.030) and worse health status than participants who did not (p=0.007).Conclusions End-of-life preferences of people with advanced COPD were heterogeneous, however, most wished to discuss it, especially those with higher educational level and worse health status.Trial registration number NTR3940.Details regarding the data analysis will be available from the corresponding author on reasonable request. Participants did not provide informed consent to share their data.