RT Journal Article SR Electronic T1 Mindfulness-based supportive therapy on reducing suffering in patients with advanced cancer: randomised controlled trial JF BMJ Supportive & Palliative Care JO BMJ Support Palliat Care FD British Medical Journal Publishing Group SP e1117 OP e1125 DO 10.1136/bmjspcare-2021-003349 VO 13 IS e3 A1 Tan, Seng Beng A1 Chee, Chung Huey A1 Ngai, Chin Fei A1 Hii, Siew Lin A1 Tan, Yi Wen A1 Ng, Chong Guan A1 Capelle, David Paul A1 Zainuddin, Sheriza Izwa A1 Loh, Ee Chin A1 Lam, Chee Loong A1 Chai, Chee Shee A1 Ng, Diana Leh Ching YR 2023 UL http://spcare.bmj.com/content/13/e3/e1117.abstract AB Objectives Suffering is common among patients with advanced cancer. The practice of mindfulness during patient care can potentially reduce suffering. We aimed to examine the efficacy of mindfulness-based supportive therapy (MBST) on reducing suffering in patients with advanced cancer.Methods We conducted a parallel-group, single-blinded, randomised controlled trial at the University of Malaya Medical Centre, Malaysia. Seventy-three patients with advanced cancer with an overall suffering score ≥4/10 based on the Suffering Pictogram were recruited and randomly assigned into either the MBST group (n=34) or the control group (n=39).Results There was a statistically significant reduction in the overall suffering score in the MBST group compared with the control group (U=432.5, median1=−2.0, median2=−1.0, z=−2.645, p=0.008). There was also significant improvement in the total Hospital Anxiety and Depression Scale score (U=483.5, median1=−4.0, median2=−3.0, z=−1.994, p=0.046), and the total Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being score (U=252.0, median1=+14.5, median2=+5.0, z=−4.549, p=0.000) in the MBST group compared with the control group.Conclusions The results provided evidence that the practice of MBST during patient care could promote positive psychosocial outcomes.Data are available on reasonable request.