PT - JOURNAL ARTICLE AU - Tan, Seng Beng AU - Chee, Chung Huey AU - Ngai, Chin Fei AU - Hii, Siew Lin AU - Tan, Yi Wen AU - Ng, Chong Guan AU - Capelle, David Paul AU - Zainuddin, Sheriza Izwa AU - Loh, Ee Chin AU - Lam, Chee Loong AU - Chai, Chee Shee AU - Ng, Diana Leh Ching TI - Mindfulness-based supportive therapy on reducing suffering in patients with advanced cancer: randomised controlled trial AID - 10.1136/bmjspcare-2021-003349 DP - 2023 Dec 01 TA - BMJ Supportive & Palliative Care PG - e1117--e1125 VI - 13 IP - e3 4099 - http://spcare.bmj.com/content/13/e3/e1117.short 4100 - http://spcare.bmj.com/content/13/e3/e1117.full SO - BMJ Support Palliat Care2023 Dec 01; 13 AB - Objectives Suffering is common among patients with advanced cancer. The practice of mindfulness during patient care can potentially reduce suffering. We aimed to examine the efficacy of mindfulness-based supportive therapy (MBST) on reducing suffering in patients with advanced cancer.Methods We conducted a parallel-group, single-blinded, randomised controlled trial at the University of Malaya Medical Centre, Malaysia. Seventy-three patients with advanced cancer with an overall suffering score ≥4/10 based on the Suffering Pictogram were recruited and randomly assigned into either the MBST group (n=34) or the control group (n=39).Results There was a statistically significant reduction in the overall suffering score in the MBST group compared with the control group (U=432.5, median1=−2.0, median2=−1.0, z=−2.645, p=0.008). There was also significant improvement in the total Hospital Anxiety and Depression Scale score (U=483.5, median1=−4.0, median2=−3.0, z=−1.994, p=0.046), and the total Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being score (U=252.0, median1=+14.5, median2=+5.0, z=−4.549, p=0.000) in the MBST group compared with the control group.Conclusions The results provided evidence that the practice of MBST during patient care could promote positive psychosocial outcomes.Data are available on reasonable request.