RT Journal Article SR Electronic T1 Mindful gratitude journaling: psychological distress, quality of life and suffering in advanced cancer: a randomised controlled trial JF BMJ Supportive & Palliative Care JO BMJ Support Palliat Care FD British Medical Journal Publishing Group SP e389 OP e396 DO 10.1136/bmjspcare-2021-003068 VO 13 IS e2 A1 Ting Ting Tan A1 Maw Pin Tan A1 Chee Loong Lam A1 Ee Chin Loh A1 David Paul Capelle A1 Sheriza Izwa Zainuddin A1 Bin Ting Ang A1 Min Ai Lim A1 Natalie Zi Lai A1 Yu Zhen Tung A1 Hway Ann Yee A1 Chong Guan Ng A1 Gwo Fuang Ho A1 Mee Hoong See A1 Mei Sze Teh A1 Lee Lee Lai A1 Ranjit Kaur Pritam Singh A1 Chee Shee Chai A1 Diana Leh Ching Ng A1 Seng Beng Tan YR 2023 UL http://spcare.bmj.com/content/13/e2/e389.abstract AB Context Numerous studies have shown that gratitude can reduce stress and improve quality of life.Objective Our study aimed to examine the effect of mindful gratitude journaling on suffering, psychological distress and quality of life of patients with advanced cancer.Methods We conducted a parallel-group, blinded, randomised controlled trial at the University of Malaya Medical Centre, Malaysia. Ninety-two adult patients with advanced cancer, and an overall suffering score ≥4/10 based on the Suffering Pictogram were recruited and randomly assigned to either a mindful gratitude journaling group (N=49) or a routine journaling group (N=43).Results After 1 week, there were significant reductions in the overall suffering score from the baseline in both the intervention group (mean difference in overall suffering score=−2.0, 95% CI=−2.7 to −1.4, t=−6.125, p=0.000) and the control group (mean difference in overall suffering score=−1.6, 95% CI=−2.3 to −0.8, t=−4.106, p=0.037). There were also significant improvements in the total Hospital Anxiety and Depression Scale score (mean difference=−3.4, 95% CI=−5.3 to −1.5, t=−3.525, p=0.000) and the total Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being score (mean difference=7.3, 95% CI=1.5 to 13.1, t=2.460, p=0.014) in the intervention group after 7 days, but not in the control group.Conclusion The results provide evidence that 7 days of mindful gratitude journaling could positively affect the state of suffering, psychological distress and quality of life of patients with advanced cancer.Trial registration number The trial was registered with the Australian and New Zealand Clinical Trials Registry (ACTRN1261800172191) and conducted in accordance with the Declaration of Helsinki.Data are available on reasonable request. Data are kept as hardcopy and soft copy by the authors.