PT  - JOURNAL ARTICLE
AU  - Raoofi, Samira
AU  - Pashazadeh Kan, Fatemeh
AU  - Rafiei, Sima
AU  - Hoseinipalangi, Zahra
AU  - Rezaei, Sepide
AU  - Ahmadi, Saba
AU  - Masoumi, Maryam
AU  - Noorani Mejareh, Zahra
AU  - Roohravan Benis, Mahshid
AU  - Sharifi, Alireza
AU  - Shabaninejad, Hosein
AU  - Kiaee, Zahra Mansour
AU  - Ghashghaee, Ahmad
TI  - Hemodialysis and peritoneal dialysis—health-related quality of life: systematic review plus meta-analysis
AID  - 10.1136/bmjspcare-2021-003182
DP  - 2023 Dec 01
TA  - BMJ Supportive & Palliative Care
PG  - 365--373
VI  - 13
IP  - 4
4099  - http://spcare.bmj.com/content/13/4/365.short
4100  - http://spcare.bmj.com/content/13/4/365.full
SO  - BMJ Support Palliat Care2023 Dec 01; 13
AB  - Background Patients with end-stage renal disease undergoing haemodialysis experience a variety of stressors leading to decreased level of quality of life (QoL). Thus, in this study, we aimed to review the current literature and identify factors affecting the health-related QoL (HRQoL) in these patients.Methods A total of 147 studies were extracted from databases of Web of Science, PubMed, Scopus, Google Scholar, and Embase published between January 2000 and December 2020. Data were analysed using R software and results were reported with reference to Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards.Results A total of 623 728 patients undergoing dialysis participated in 147 studies in which QoL was assessed by means of two valid questionnaires, including Short-Form 36 (SF-36) and Kidney Disease Quality of Life (KDQOL)-short form V.1.3. Total HRQoL score for patients undergoing dialysis measured by KDQOL was 64.25 (95% CI 55.67 to 72.82). Based on SF-36, the mean score of mental health items was higher than the mean score of physical health condition. Furthermore, meta-regression based on the geographical place of residence revealed that the highest QoL in patients was observed in Japan, 66.96 (95% CI 63.65 to 70.28) and Brazil, 58.03 (95% CI 53.45 to 62.6).Conclusion Studies conducted on HRQoL among patients undergoing dialysis recommend useful strategies to clinicians, letting them assess patients’ QoL in terms of a wide range of physical, mental and environmental aspects.