PT - JOURNAL ARTICLE AU - Phillips, Iain AU - Allan, Lindsey AU - Hug, Adele AU - Westran, Naomi AU - Heinemann, Claudia AU - Hewish, Madeleine AU - Mehta, Ajay AU - Saxby, Helen AU - Ezhil, Veni TI - Nutritional status and symptom burden in advanced non-small cell lung cancer: results of the dietetic assessment and intervention in lung cancer (DAIL) trial AID - 10.1136/bmjspcare-2020-002838 DP - 2023 Oct 01 TA - BMJ Supportive & Palliative Care PG - e213--e219 VI - 13 IP - e1 4099 - http://spcare.bmj.com/content/13/e1/e213.short 4100 - http://spcare.bmj.com/content/13/e1/e213.full SO - BMJ Support Palliat Care2023 Oct 01; 13 AB - Introduction European Society for Clinical Nutrition and Metabolism guidelines recommend that patients with cancer should be screened for malnutrition at diagnosis. The dietetic assessment and intervention in lung cancer study investigated the nutritional status of patients with non-small cell lung cancer (NSCLC) and the need for dietetic intervention.Methods In this observational cohort pilot study, patients with stage 3b and 4 NSCLC were assessed prior to starting first line systemic anticancer therapy (SACT) with a range of measurements and questionnaires. We report the outcomes related to the Patient Generated Subjective Global Assessment tool (PG-SGA),Results 96 patients were consented between April 2017 and August 2019. The PG-SGA identified that 78% of patients required specialist nutritional advice; with 52% patients having a critical need for dietetic input and symptom management. Results were dominated by symptom scores. As a screening test, one or more symptoms or recent weight loss history had a sensitivity of 88% (95% CI 78.44% to 94.36%) and specificity of 95.24% (95% CI 76.18% to 99.88%) for need for dietetic intervention.Conclusion A large proportion of patients with NSCLC have a high symptom burden and are at risk of malnutrition prior to starting SACT and would benefit from dietetic review. It is imperative that oncologists and healthcare professionals discuss weight loss history and symptoms with lung cancer patients to correct nutritional deficiencies and resolve symptoms prior to starting treatment.Data are available on reasonable request. Deidentified data are currently held by Royal Surrey County Hospital Research department.