PT - JOURNAL ARTICLE AU - Barbara Clyne AU - Sinead M O’Neill AU - Daniel Nuzum AU - Michelle O'Neill AU - James Larkin AU - Máirín Ryan AU - Susan M Smith TI - Patients' spirituality perspectives at the end of life: a qualitative evidence synthesis AID - 10.1136/bmjspcare-2019-002016 DP - 2022 Oct 01 TA - BMJ Supportive & Palliative Care PG - e550--e561 VI - 12 IP - e4 4099 - http://spcare.bmj.com/content/12/e4/e550.short 4100 - http://spcare.bmj.com/content/12/e4/e550.full SO - BMJ Support Palliat Care2022 Oct 01; 12 AB - Background Understanding patient perceptions of their spiritual needs when approaching the end of life is essential to support the delivery of patient-centred care.Aim To conduct a qualitative evidence synthesis on spirituality and spiritual care needs at the end of life in all healthcare settings from the patients’ perspective.Design Studies were included where they were primary qualitative studies exploring spirituality in patients with a life expectancy of 12 months or less in any setting. Two reviewers independently screened titles, extracted data and conducted methodological quality appraisal. A thematic synthesis was conducted. Grading of Recommendations, Assessment, Development and Evaluation (GRADE) - Confidence in the Evidence from Reviews of Qualitative research (CERQual) was used to summarise the certainty of the evidence.Data sources Six databases (Medline, Embase, Cochrane, CINAHL, PsycINFO, Applied Social Science Index and Abstracts) were searched from inception up to January 2019.Results Fifty papers (42 unique datasets), incorporating data from 710 patients were included. Studies recruited from a mix of inpatient, outpatient, hospice and community settings across 12 different countries. Three overarching themes were generated: the concept of spirituality, spiritual needs and distress, and spiritual care resources. Relationships were an intrinsic component of spirituality.Conclusion Meeting patients’ spiritual needs is an integral part of end-of-life care. This work emphasises that supporting relationships should be a central focus of spiritual care for patients at the end of life.PROSPERO registration number CRD42019122062