RT Journal Article SR Electronic T1 Dexmedetomidine withdrawal syndrome and opioid sensitivity JF BMJ Supportive & Palliative Care JO BMJ Support Palliat Care FD British Medical Journal Publishing Group SP bmjspcare-2020-002705 DO 10.1136/bmjspcare-2020-002705 A1 Lana Ferguson A1 Stacey Hooper YR 2020 UL http://spcare.bmj.com/content/early/2021/09/26/bmjspcare-2020-002705.abstract AB This case report describes the use of dexmedetomidine for refractory cancer pain management in a patient with significant pelvic disease due to metastatic urothelial cancer. Specifically, the management of increased opioid sensitivity secondary to dexmedetomidine is discussed. Further, the phenomenon of dexmedetomidine withdrawal syndrome and our management of this is addressed.