PT - JOURNAL ARTICLE AU - Lana Ferguson AU - Stacey Hooper TI - Dexmedetomidine withdrawal syndrome and opioid sensitivity AID - 10.1136/bmjspcare-2020-002705 DP - 2020 Dec 22 TA - BMJ Supportive & Palliative Care PG - bmjspcare-2020-002705 4099 - http://spcare.bmj.com/content/early/2021/09/26/bmjspcare-2020-002705.short 4100 - http://spcare.bmj.com/content/early/2021/09/26/bmjspcare-2020-002705.full AB - This case report describes the use of dexmedetomidine for refractory cancer pain management in a patient with significant pelvic disease due to metastatic urothelial cancer. Specifically, the management of increased opioid sensitivity secondary to dexmedetomidine is discussed. Further, the phenomenon of dexmedetomidine withdrawal syndrome and our management of this is addressed.