TY - JOUR T1 - Fatigue and malignant pleural effusions JF - BMJ Supportive & Palliative Care JO - BMJ Support Palliat Care SP - 305 LP - 305 DO - 10.1136/bmjspcare-2021-002955 VL - 11 IS - 3 AU - Avinash Aujayeb AU - Donna Wakefield Y1 - 2021/09/01 UR - http://spcare.bmj.com/content/11/3/305.abstract N2 - Dear EditorsWe completely agree with Twose et al 1 that until now the primary focus in both clinical practice and trials has been on interventions in malignant pleural effusions (MPEs), tailored to mitigating breathlessness and preventing admissions, with little consideration of other factors potentially of greater priority to the patient. We were encouraged to see that constitutional symptoms such as fatigue and anorexia were investigated, but disappointed that the effects of aspiration were not sustained at 7 days. Our interest lies in fatigue in MPEs. Cancer-related fatigue is well described and is a subjective symptom experienced by patients at all stages of disease and can occur during treatment, in advanced disease and in disease-free survivors.2 Approximately 40% … ER -