TY - JOUR T1 - Hemodialysis and peritoneal dialysis—health-related quality of life: systematic review plus meta-analysis JF - BMJ Supportive & Palliative Care JO - BMJ Support Palliat Care DO - 10.1136/bmjspcare-2021-003182 SP - bmjspcare-2021-003182 AU - Samira Raoofi AU - Fatemeh Pashazadeh Kan AU - Sima Rafiei AU - Zahra Hoseinipalangi AU - Sepide Rezaei AU - Saba Ahmadi AU - Maryam Masoumi AU - Zahra Noorani Mejareh AU - Mahshid Roohravan Benis AU - Alireza Sharifi AU - Hosein Shabaninejad AU - Zahra Mansour Kiaee AU - Ahmad Ghashghaee Y1 - 2021/07/22 UR - http://spcare.bmj.com/content/early/2021/07/22/bmjspcare-2021-003182.abstract N2 - Background Patients with end-stage renal disease undergoing haemodialysis experience a variety of stressors leading to decreased level of quality of life (QoL). Thus, in this study, we aimed to review the current literature and identify factors affecting the health-related QoL (HRQoL) in these patients.Methods A total of 147 studies were extracted from databases of Web of Science, PubMed, Scopus, Google Scholar, and Embase published between January 2000 and December 2020. Data were analysed using R software and results were reported with reference to Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards.Results A total of 623 728 patients undergoing dialysis participated in 147 studies in which QoL was assessed by means of two valid questionnaires, including Short-Form 36 (SF-36) and Kidney Disease Quality of Life (KDQOL)-short form V.1.3. Total HRQoL score for patients undergoing dialysis measured by KDQOL was 64.25 (95% CI 55.67 to 72.82). Based on SF-36, the mean score of mental health items was higher than the mean score of physical health condition. Furthermore, meta-regression based on the geographical place of residence revealed that the highest QoL in patients was observed in Japan, 66.96 (95% CI 63.65 to 70.28) and Brazil, 58.03 (95% CI 53.45 to 62.6).Conclusion Studies conducted on HRQoL among patients undergoing dialysis recommend useful strategies to clinicians, letting them assess patients’ QoL in terms of a wide range of physical, mental and environmental aspects. ER -