You are here

  • Home
  • Online First
  • Physical activity and prognosis and factors associated with low physical activity in patients with advanced or recurrent lung cancer: a retrospective, observational study

Article Text

Article menu
Download PDFPDF
Short report
Physical activity and prognosis and factors associated with low physical activity in patients with advanced or recurrent lung cancer: a retrospective, observational study
  1. Takuya Fukushima1,
  2. Utae Katsushima2,
  3. Naoya Ogushi3,
  4. Kimitaka Hase4 and
  5. Jiro Nakano1
  1. 1Faculty of Rehabilitation, Kansai Medical University, Hirakata, Osaka, Japan
  2. 2Department of Thoracic Oncology, Kansai Medical University, Hirakata, Osaka, Japan
  3. 3Department of Rehabilitation, Kansai Medical University Hospital, Hirakata, Osaka, Japan
  4. 4Department of Physical Medicine & Rehabilitation, Kansai Medical University, Hirakata, Osaka, Japan
  1. Correspondence to Dr Jiro Nakano, Faculty of Rehabilitation, Kansai Medical University, Hirakata-shi, Osaka, 573-1136, Japan; nakanoj{at}hirakata.kmu.ac.jp

Abstract

Objectives To investigate the relationship between physical activity and prognosis, and the significant factors associated with physical activity in patients with advanced or recurrent lung cancer.

Methods This retrospective, observational study enrolled 50 outpatients with lung cancer who received chemotherapy. Patients were evaluated for physical function, physical activity (International Physical Activity Questionnaire-Short Form), and nutritional status (Mini Nutritional Assessment-Short Form [MNA-SF]). The relationship between physical activity and prognosis was examined using the log-rank test and Cox proportional hazards model. Multivariate logistic regression analysis was performed to examine factors associated with low physical activity. A receiver operating characteristic curve was used to calculate the MNA-SF cut-off value for low physical activity.

Results Low physical activity was significantly associated with survival (HR, 4.35; 95% confidence interval [CI], 1.16–16.27; p=0.029). The MNA-SF was a significant factor associated with low physical activity (OR, 0.71; 95% CI, 0.52 to 0.98; p=0.038). The MNA-SF cut-off value for low physical activity was 9.5 points.

Conclusions Low physical activity may be a prognostic factor in lung cancer, with nutritional status associated with low physical activity. Regular assessments using the MNA-SF cut-off and physical activity interventions considering nutrition are needed in clinical practice.

  • Lung
  • Rehabilitation
  • Palliative Care
  • Supportive care

https://doi.org/10.1136/spcare-2024-005122

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • Contributors TF: conceptualisation, methodology, software, validation, formal analysis, investigation, data curation, writing—original draft, visualisation, funding acquisition. UK: investigation, resources, data curation, writing—review and editing, supervision, project administration. NO: investigation. KH: writing—review and editing, supervision. JN: investigation, writing—review and editing, supervision.

    • Funding This work was supported in part by JSPS KAKENHI (grant number 22K17603).

    • Competing interests The authors declare no potential conflicts of interest with respect to the research, authorship or publication of this article.

    • Provenance and peer review Not commissioned; internally peer reviewed.

    • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.