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Efficacy of metyrapone for symptoms of adrenocortical carcinoma
  1. Yuka Okuda,
  2. Toshiyuki Kuriyama and
  3. Tomoyuki Kawamata
  1. Department of Anesthesiology, Wakayama Medical University, Wakayama, Japan
  1. Correspondence to Dr Yuka Okuda, Department of Anesthesiology, Wakayama Medical University, Wakayama, Japan; yuuka-o{at}


Elevated cortisol by adrenocortical carcinoma leads to a variety of symptoms. We report on the efficacy of metyrapone in treatment of a variety of distressing symptoms caused by elevated cortisol in a patient who refused advanced treatment for adrenocortical carcinoma.

  • supportive care
  • terminal care

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  • Contributors All authors critically reviewed and revised the manuscript draft and approved the final version for submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.