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Health-related quality of life, patient-centred communication and self-efficacy in ovarian cancer: a mediation analysis
  1. Rachel A Pozzar1,2,
  2. Niya Xiong3,
  3. Emanuele Mazzola3,
  4. Alexi A Wright1,2,
  5. Barbara A Goff4,
  6. James A Tulsky2,5,
  7. Marilyn J Hammer1,2 and
  8. Donna L Berry6
  1. 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
  2. 2Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
  3. 3Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
  4. 4Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA
  5. 5Department of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
  6. 6Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, Washington, USA
  1. Correspondence to Dr Rachel A Pozzar, Dana-Farber Cancer Institute, Boston, MA 02115, USA; rachel_pozzar{at}dfci.harvard.edu

Abstract

Objective To assess the role of self-efficacy as a mediator of the association between patient-centred communication (PCC) and health-related quality of life (HRQoL) in a sample of participants with ovarian cancer.

Methods English-speaking adults with ovarian cancer completed a cross-sectional survey. We assessed self-efficacy with the Self-Efficacy for Managing Chronic Disease scale, PCC with the Patient-Centred Communication in Cancer Care-36, and HRQoL with the Functional Assessment of Cancer Therapy-General. We used the PROCESS macro to calculate regression coefficients for the total effect of PCC on HRQoL and direct effect of PCC on HRQoL. We calculated a 95% CI for the indirect effect of PCC on HRQoL using 10 000 bootstrapped samples.

Results The total effect of PCC on HRQoL (9.47, 95% CI 6.21 to 12.74) was greater than the direct effect of PCC on HRQoL (3.47, 95% CI 0.73 to 6.21). The indirect effect of PCC on HRQoL was 6.00 (95% CI 3.56 to 8.95). Self-efficacy explained approximately 63.4% of the association between PCC and HRQoL.

Conclusions Self-efficacy partially mediated the association between PCC and HRQoL. Self-efficacy is a potential target for communication interventions that aim to improve HRQoL. Research to validate this finding in the setting of a randomised trial is warranted.

  • Communication
  • Quality of life
  • Other cancer
  • Supportive care

http://dx.doi.org/10.1136/spcare-2022-004029

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    Footnotes

    • Twitter @rpozzar

    • Contributors RP: conceptualisation; data curation; data analysis; writing—original draft. NX and EM: Data analysis; writing—review and editing. BAG and DLB: conceptualisation; data curation; writing—review and editing. AW, JAT and MJH: conceptualisation; writing—review and editing.

    • Funding This work was supported by an American Cancer Society Postdoctoral Fellowship (133063-PF-19-102-01-CPPB) and a Gordon and Betty Moore Foundation Society for Medical Decision Making Fellowship in Medical Decision Making (GBMF7853).

    • Disclaimer The funding sources had no involvement in the study design; in the collection, analysis, or interpretation of data; in the writing of the report; or in the decision to submit the article for publication.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; internally peer reviewed.