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Research focusing on quality of life (QoL) in children and adolescents with high-risk malignancy (HRM) is of primary importance. As most of these patients are treated in low-income and middle-income countries,1 publications from Central America are of great value. We are thankful to Salaverria et al. for their work addressing this complex and key subject.2
Patients with HRM were defined by Mahmood et al. as having >50% risk of death due to their disease. These patients should receive optimal symptom management and optimal disease-directed therapies to increase both their survival and QoL. To …
Contributors All authors contributed equally to drafting and revising manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.
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