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Naloxegol for opioid-induced sphincter of Oddi spasm/dysfunction
  1. Andrew Neil Davies and
  2. Charlotte Leach
  1. Supportive & Palliative Care, Royal Surrey County Hospital, Guildford, UK
  1. Correspondence to Dr Andrew Neil Davies, Supportive & Palliative Care, Royal Surrey County Hospital, Guildford GU2 7XX, UK; adavies12{at}


The paper describes a case report of a patient with a significant history of opioid-induced dysfunction of the sphincter of Oddi, who required morphine sulfate to manage oral mucositis pain, and who was successfully treated with concomitant oral naloxegol (Moventig: Kyowa Kirin, Galashiels, UK).

  • analgesics, opioid
  • naloxegol
  • narcotic antagonists
  • sphincter of Oddi

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  • Contributors AND wrote the initial draft of the paper, and CL contributed to the final version of the paper. Both were involved in the care of the patient.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests AND has received honoraria for lecturing and for attending advisory boards, and research funding from Kyowa Kirin. CL has received an honorarium for lecturing from Kyowa Kirin.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.