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57 Evidence into practice: novel approaches to underpinning evidence-based innovations in care
  1. Mala Mann1,
  2. Annmarie Nelson2,
  3. Amanda Woodward2,
  4. Ishrat Islam2 and
  5. Anthony Byrne2
  1. 1Specialist Unit for Review Evidence, Cardiff University, UK
  2. 2Marie Curie Palliative Care Research Centre (MCPCRC), Division of Population Medicine, School of Medicine, Cardiff University, UK


Background Developing and implementing novel models of care requires a robust approach to identifying and assessing existing evidence. Rapid reviews have emerged as an efficient approach. There is a growing number of rapid review ‘methods’ but no accepted standardised methodology. We describe the methodological options and an example the Palliative Care Evidence Review Service (PaCERS) where streamlined systematic review methodology is used to conduct rapid reviews requested by clinicians/clinical services.

Aims To describe evidence synthesis options including PaCERS for producing rapid evidence summaries on questions of direct importance to service delivery. To identify related methodological challenges.

Methods We examine various rapid review methods and describe in full PaCERS methodology. This uses a focussed search strategy across a limited set of databases and other sources. Study selection data extraction and critical appraisal are performed independently by at least two reviewers. Results are published online using a template co-produced with users which describes key clinical messages evidence quality and summaries of included studies.

Results We will describe the pros and cons of conducting rapid reviews and highlight methodology development unique to PaCERS. We will discuss specific issues encountered during the review process to produce rigorous reviews in a short time frame for palliative services.

Conclusion Rapid reviews have tremendous methodological variation however they are an important tool for evidence-informed decision making especially when time resource constraints and health needs are an issue. Therefore using rapid reviews can be used in implementing new models of palliative care.


  1. . Wales Cancer Research Centre. Palliative Care Evidence Review Service (PaCERS)2016. Available at: [Accessed: 30 May 2018]

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