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P-114 End-stage chronic liver disease: a look at the last year of life
  1. Ruth Yates,
  2. Eliana Saffouri,
  3. Alix Morieux and
  4. Fiona Finlay
  1. Queen Elizabeth University Hospital, Glasgow, UK


Introduction Liver disease is the fifth most common cause of death in the UK.1 Patients with chronic liver disease (CLD) and its complications present frequently to hospital; when their disease reaches end-stage, their supportive and palliative care needs can be high.2 In this study we describe the last year of patients‘ lives with CLD to identify opportunities for concurrent palliative care involvement in the future.

Methods We performed a comprehensive retrospective casenote analysis of patients who died of CLD (or complications) in a teaching hospital over a period of 12 months. Caldicott approval was obtained.

Results Reasons for admission in the cases were varied, but could all be attributed to decompensation of CLD. Alcohol was the causative factor in the majority of cases. Almost every patient had DNACPR in place when they died. Patients died both on the ward and in level 2/3 settings. A minority met the specialist palliative care team. Many patients had active interventions and investigations within 24 hours of death.

Conclusions We were able to perform a detailed examination of the hospital admissions of this cohort of patients during the last year of life. We identified alcohol as a contributing factor in the majority of cases, however this did not appear to prejudice clinicians from admitting patients to level 2/3 care. It appears that DNACPR is considered appropriately, however patients are still having investigations and non-symptomatic medications even after death is recognised as imminent. More work is needed to identify whether early palliative care involvement could be helpful to these patients.


  1. . British Association for the Study of the Liver and British Society of Gastroenterology. A time to act: improving liver health and outcomes in liver disease. The National Plan for Liver Services UK, 2009.

  2. . Hansen L, Sasaki A, Zucker B. End-stage liver disease: challenges and practice implications. Nurs Clin North Am2010;45:411–26.

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