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Safety and feasibility of exercise interventions in patients with advanced cancer: a systematic review
Heywood R, McCarthy AL, Skinner TL. Support Care Cancer. 2017; 25: 3031–3050.
This systematic review evaluated adverse events during exercise training and attendance and adherence rates in patients with advanced cancer. Twenty-five studies (1088 patients) up to December 2015 were included (16 randomised controlled trials and 9 prospective observational cohort trials). Mean age ranged from 18 to 88 years old. Twenty-two studies (88%) reported adverse events, with six patients (0.55%) experiencing a minor exercise-related musculoskeletal adverse event. Nine studies reported attendance, which was between 59% and 100%; nine studies reported adherence rates, which was between 65% and 89%. Limitations of this review include the heterogeneity of the exercise interventions and the …
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.