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P 006
  1. S Latter1,
  2. J Hopkinson2,
  3. E Lowson1,
  4. A Richardson1,
  5. J Hughes2,
  6. S Duke1,
  7. S Anstey2,
  8. M Bennett3,
  9. C May1,
  10. P Smith4 and
  11. J Hughes1
  1. 1Faculty of Health Sciences University of Southampton
  2. 2Cardiff School of Healthcare Sciences Cardiff University
  3. 3School of Medicine, University of Leeds
  4. 4Southampton Statistical Sciences Research Institute, University of Southampton


Introduction Family carers need support with managing end-of-life pain medicines, yet no UK research has developed and tested interventions to help with this.

We have recently completed a Phase I-II feasibility study, funded by Dimbleby Marie Curie, to test a new intervention: Cancer Carer Medicines Management (CCMM).

Aim(s) and method(s) To test the feasibility, acceptability and efficacy of CCMM to improve carers' knowledge, beliefs, and self-efficacy for pain medicines management.

Phase I We used an incremental, multi-method approach to develop CCMM including a systematic review of interventions for carer end-of-life medicines management, interviews and action research workshops. Phase II: A two arm, cluster randomised feasibility trial of CCMM with outcomes at baseline, 1 and 4 weeks post-intervention and a qualitative sub-study of CCMM acceptability and trial methods, with carer interviews conducted 1 and 4 weeks post-intervention, and with nurses on study completion.

Results Phase I enabled us to develop an evidence-based, clinically applicable intervention. In Phase II we recruited, randomised and trained nurses to use CCMM at two sites. 16 patient-carer dyads were recruited to the study; 8 dyads completed the study protocol. 10 of 12 study nurses took part in an interview. We will present results on study feasibility and acceptability including: the randomisation process; recruitment and attrition rates; key factors that promoted or inhibited routine utilization of CCMM by nurses and carers; and obstacles to the trial process.

Conclusions A newly developed intervention for carers was tested in a feasibility trial. Important lessons were learned to inform the design and evaluation of future research in this area.

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